Peter Attia· MD
if there is a mutant in The Binding domain of apple b you have something that we call FH or familial defective EPO B which is basically the same
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The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
if there is a mutant in The Binding domain of apple b you have something that we call FH or familial defective EPO B which is basically the same
Every Sunday: the week’s new conflicts and verdict changes — and nothing else.
Native comments, Twitter mentions, and Reddit threads about this claim — surfaced together so the conversation isn't fragmented across platforms.
Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
Would love a "what would change this verdict" RSS feed. Sign me up if it exists.
it's one of the reasons people with FH have such cuz they have very big particles and their high apob is due to defective LDL receptors but it's also due to defective attachment to LDL receptors because the apob is no longer in the proper confirmation