Paul Saladino· MD
there's just no correlation between uh detected LDL levels at Baseline and resulting plaque
The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
there's just no correlation between uh detected LDL levels at Baseline and resulting plaque
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Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
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When you look at the data again, when they did this regression analysis and they looked at the factors that predicted did your plaque go up during the year, LDL and APOB had no relationship to whether or not your plaque increased. The only thing that they found that had a relationship was how much plaque you had on the first scan.