Peter Attia· MD
I have not yet seen a case of that now admittedly my practice is not large but we're certainly looking for it when we see people with high HDL cholesterol typically you know north of 90.
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The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
I have not yet seen a case of that now admittedly my practice is not large but we're certainly looking for it when we see people with high HDL cholesterol typically you know north of 90.
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Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
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The LDL cholesterol story is actually relatively straightforward we don't know when we measure an elevated HDL cholesterol if it is a biomarker of something good that is happening IE hdl's delipidating foam cells macrophages things like that or if it's a bad thing I went really down the rabbit hole three years ago on the literature of people with elevated HDL cholesterol who were developing premature ascvd so deposited that these people with elevated hdlc that was actually a biomarker for very dysfunctional hdls yeah those are people with srb1 mutations exactly