Paul Saladino· MD
There is a LARGE amount of evidence to suggest that being insulin sensitive massively attenuates the increase in cardiovascular risk seen with higher ApoB levels.
The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
There is a LARGE amount of evidence to suggest that being insulin sensitive massively attenuates the increase in cardiovascular risk seen with higher ApoB levels.
Every Sunday: the week’s new conflicts and verdict changes — and nothing else.
Native comments, Twitter mentions, and Reddit threads about this claim — surfaced together so the conversation isn't fragmented across platforms.
Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
Would love a "what would change this verdict" RSS feed. Sign me up if it exists.
if you have a low fasting insulin if you have a six pack or even if you don't have a six-pack but you know you don't have a lot of visceral fat I don't think the same process of pulling that LDL into that endothelium into that sub-intominal layer of the arterial wall is happening and in that population of people more April B does not necessarily mean more atherosclerosis