The evidence is convergent. Multiple independent sources reach the same conclusion, the underlying mechanism is well-characterized, and even the field's most cautious voices treat it as worth doing.
on the x- axis you have LDL concentration and on the y- axis you have mortality or cardiovascular mortality and as you pointed out these lines are just going straight down meaning as LDL cholesterol is going down either genetically or through drugs cardiovascular mortality is going down.
Every Sunday: the week’s new conflicts and verdict changes — and nothing else.
Native comments, Twitter mentions, and Reddit threads about this claim — surfaced together so the conversation isn't fragmented across platforms.
Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
Would love a "what would change this verdict" RSS feed. Sign me up if it exists.
again aend randomization study is basically a lifetime randomized control trial I mean it is for that the highest quality of evidence that we have um and people will say well there's plot tropy whatever okay nothing's perfect but again we have mechanism penetrates the endothelium we have animal studies showing a dose response we have actually some human randomized control trials that do show an effect and we have the cohort studies that show an effect when it's when it's long enough and they use appropriate um covariates so we have all those things lining up and we have the long-term randomized control trials so I'm just like I don't need I I don't know what other kind of evidence you need to like convince you like there's just not any like I don't what else we can give you you know