Peter Attia· MD
the rare genetics are probably not going to be in as informative certainly not as informative as p69 which is I think you know stands alone in terms of the quality of it its informativeness both as a rare disease mutation but also as a common disease variant but the genes that underly the Comm variation in these phenotypes are I think going to be very interesting and so I think that's where we're focused because the rare disease the the single gene mutations you know one of the most common the underly the disease underlying fld2 is a mutation in lamin I mean we know that this leads to pereria it leads to cardiopathy it leads to you know muscular distrophy it leads to lipo distopy you know it's a whole it's a complicated mess of a protein that's expressed in the nuclear lamina it's it's a it's hard to kind of imagine that common variation in that Gene is going to lead to to yeah problems it might but it's not it's not obvious