Rhonda Patrick· PhD
So the specific polyphenols in coffee, decaf or caffeinated... So irrespective of caffeine, it's just it's the polyphenols. Yeah. They triggered protein deacetylation, which is one of the triggers for autophagy.
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The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
So the specific polyphenols in coffee, decaf or caffeinated... So irrespective of caffeine, it's just it's the polyphenols. Yeah. They triggered protein deacetylation, which is one of the triggers for autophagy.
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And doing exercise. And when you're eating... Sorry, throughout the day, when you're not eating, do you drink coffee? Yes. And there's polyphenols in coffee that actually... Yes, we published a study in mice giving them a non-toxic dose of caffeinated or decaffeinated coffee with a drinking water continuously. And we could show that this was magnificently inducing autophagy. Like caffeine independent fasting. Right, totally independent caffeine, so just the polyphenols.