Low-dose naltrexone (LDN) has shown efficacy in some patients with complex regional pain syndrome and multiple sclerosis.

“complex regional pain syndrome it has had a that's a very tragic pain condition that is a neuropathic pain condition and we see a fair amount of I've got a clinical trial i'm just wrapping up on that using lowdos nrexone um funded by the RSDSA association and another is actually multiple sclerosis they've used it in and they found some reduction in reoccurrences of MS i think they did that at UCSF um or UCLA but it's in these weird neurodeenerative type conditions um where they're seeing some help”