Prion-based diseases are transmissible and characterized by pathogenic misfolded proteins that propagate, leading to motor and cognitive symptoms, and eventually early death with no known treatment.

“so so there's this uh this group of uh Prime based diseases and they differ from species to species but it's certainly there seems to be some evidence that I think they can kind of bear the zoonotic right they can try and transmit from once they are so we would call it quotes from Jacob disease in humans BSE and cows um scrapey um in sheep um and the the ideas is essentially this almost like pathogenic misfolded protein which which can sort of like propagate and associated with that you get all kinds of motor cognitive uh symptoms and then eventually early death and there's there's no treatment as far as We Know”