Paul Saladino· MD
a PO II is very important because it transfers cholesterol between astrocytes and neurons
The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
a PO II is very important because it transfers cholesterol between astrocytes and neurons
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Native comments, Twitter mentions, and Reddit threads about this claim — surfaced together so the conversation isn't fragmented across platforms.
Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
Would love a "what would change this verdict" RSS feed. Sign me up if it exists.
what is very interesting is if my memory serves me correctly I believe it's only a single amino acid substance it's between each of these in other words one amino acid difference between the one made by the three isopor and the for isopor results in what you just said which is individuals who have the apoe4 gene have an apoe4 protein that wraps their brain lipoproteins that gives it less affinity for doing this job of transferring cholesterol from astrocytes to neurons