Observational studies in the 1980s and 1990s suggested women on hormone therapy had lower rates of heart disease, less cognitive decline, and lower all-cause mortality compared to non-users.

“yes so back in the 1980s and 1990s there were several observational studies these are not randomized clinical trials but large observational studies looking at women who chose to be on hormone therapy or whom doctors were prescribing hormone therapy for and they did tend to have lower rates of heart disease in those studies compared to women not using hormone therapy they also seem to have more favorable outcomes such as less cognitive decline line lower all-cause mortality rates they were generally doing better”