Peter Attia· MD
homocysteine is an is an amino acid in the blood that is an independent risk factor so if you have high homocysteine you are more likely to have brain shrinkage over time and impaired memory function
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The evidence is convergent. Multiple independent sources reach the same conclusion, the underlying mechanism is well-characterized, and even the field's most cautious voices treat it as worth doing.
homocysteine is an is an amino acid in the blood that is an independent risk factor so if you have high homocysteine you are more likely to have brain shrinkage over time and impaired memory function
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So it suggested that this is a causal relationship, that it is a mediator of cognitive, well, of change in cerebral volume as well as cognitive decline.
So we want to know your homocysteine, the marker of methylation. If you're not methylated appropriately and your homocysteine is high, then you are at increased risk for neurodegeneration. And of course, it's been published that you have a more rapid decline in your cerebral grey matter volume and hippocampal volume if you have a high homocysteine.
But then if you improve the homocysteine and brought it back to normal and they're looking at less than seven as being normal not less than 13, which is often used in the labs.