The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
Now interestingly, for the ApoE4s what we typically suggest, and this was actually originally suggested by Julie G. who started the website, apoe4.info. You essentially start with using the MCT oil to help you get your ketosis, but then switch after a month or two to more monounsaturates and polyunsaturates.
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Native comments, Twitter mentions, and Reddit threads about this claim — surfaced together so the conversation isn't fragmented across platforms.
Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
Would love a "what would change this verdict" RSS feed. Sign me up if it exists.
I think that a more moderate style Mediterranean-like low-carb/ketogenic diet with supplementation in the form of things like omega-3 fatty acids, MCT oils. The fatty acids comprising the diet should be more along the lines of monounsaturated fats and not so much heavy saturated fats, which in the context of APOE4 is probably not a good thing to chronically maintain a state of ketosis with superhigh saturated fat.
But I think the take-home message is that a diet that's very...like super-restrictive and high in fat is probably not ideal for APOE4 patients, and adding ketones in the form of exogenous ketones could probably be ideal.