Peter Attia· MD
they concluded that a high level of education hypertension control protected apoe4 carriers from dementia compared to 844 carriers who had less education and worse blood pressure control
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The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
they concluded that a high level of education hypertension control protected apoe4 carriers from dementia compared to 844 carriers who had less education and worse blood pressure control
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apo e4 significantly increases your risk for the development of alzheimer's disease it appears but what's interesting is that if you are apoe4 but you are normal tensive you don't necessarily have an increased risk of alzheimer's disease
if you are apoe4 but you are hypertensive then your alzheimer's disease risk is far higher so in other words there seems to be an interaction a gene by cardiovascular disease interaction that leads that genotype to predispose you to alzheimer's disease