Cold water immersion and cryotherapy both induce a robust release of norepinephrine, though they differ in their ability to reduce body temperature.

“Cryotherapy at temperatures - 166 degrees F for 2 minutes boosted norepinephrine 2- to 3 -fold.”

“both cold water immersion & cryotherapy have been shown to robustly release norepinephrine between 2-5-fold!”

“Cryo & cold-water immersion (up to 5-fold) being among them!”

“Just 20 sec in cold water can boost it 2-fold!”

“Other studies have found that 20 seconds at 40 F can increase norepinephrine 2-fold over baseline levels.”

“in one study women either swam in 35.6 degree fahrenheit water for 20 seconds or underwent cryotherapy at temperatures 166 degrees fahrenheit for two minutes they did this three times per week for 12 weeks both groups of women showed two to three-fold increases in their circulating norepinephrine after each exposure session”

“the most common methods are cold water immersion and cryotherapy they differ in their ability to reduce body temperature but they both seem to induce a robust release of norepinephrine”

“But if you just go in there for 20 seconds, if you really want to be efficient, that also is associated with a two-fold increase in norepinephrine.”