We can't find evidence that holds up here. Proponents are reasoning from mechanism or analogy rather than direct human data, and the most credible skeptics raise objections we can't dismiss.
so if a person is taking a collagen protein because they believe that it will disproportionately help them increase the strength of their connective tissue the data would say that that is not correct at least in the presence of an exercising individual
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if there are people listening to this who are just using collagen as their supplemental protein Source they're undoubtedly compromising myofibrillar muscle protein synthesis because as you said they're basically just getting a lot of Proline and Glycine and they're probably really missing out on Lucine lysine methionine and the other amino acids that are far more potent it's a very low quality protein from the perspective amino acid balance yes yes
so if a person is taking a collagen protein because they believe that it will disproportionately help them increase the strength of their connective tissue the data would say that that is not correct at least in the presence of an exercising individual yes over over five hours I guess to be fully complete
I think we we so in muscle I think that the availability of the amino acids is not restricting the increase after uh physical activity because after physical activity we see the connective tissue protein synthesis rates go up but it doesn't seem to be depend on the amount of protein or collagen that you provide so I think there it's not limited at least not in the first few hours after exercise
and in muscle that is um a lot of it is collagen uh but if we get a a fraction of the muscle is the connective connective proteins and of those connective proteins about 5% is collagen and so we were interested to see collagen ingestion will actually stimulate that specific fraction in muscle now so far um Studies have not shown increase in muscle protein synthesis when you ingest collagen now why could that be the case because it responds to high quality protein but not to collagen now collagen is is from a from amino acid composition not a very high quality protein because almost 50% is composed of uh of Proline and glycine and so it has a lot less essential amino acids and so if you give collagen protein you generally don't see increase in mixed muscle proteins we've done a study to see whether it increases connective protein in muscle we don't see it at least not with the with the the 20 grams or or the 30 gr amounts