Gene editing for sickle cell disease modifies a different gene to allow the fetal hemoglobin gene to turn on, rather than directly correcting the mutation.

“um and and the the way the treatment works is that uh for CYO cell patients it's been found that for some individuals who have the C cell mutation um if they also carry another mutation or or if they somehow is able to express the fetal version of hemoglobin mhm then their C cell symptoms are much much less and so for treating CLE cell patients with Gene editing the therapy actually goes and modifies a different Gene um sort of modulates his expression to then allow the feto hemoglobin Gene to turn on”