Paul Saladino· MD
mostly nanomolar range concentrations of curcumin are achieved with massive dosing it is very difficult nearly impossible to get micromolar range dosing of curcumin or micromolar levels of curcumin in the human body
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The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
mostly nanomolar range concentrations of curcumin are achieved with massive dosing it is very difficult nearly impossible to get micromolar range dosing of curcumin or micromolar levels of curcumin in the human body
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curcuminoids including curcumin in turmeric are very poorly bioavailable because your body wants to detoxify them and get them out of your body as quickly as possible so in order to get meaningful doses that actually achieve any physiological effect which i would argue is negative in the first place uh many of these need to be packaged this must be packaged with either piperine and we'll talk about the dangers of that later on in this video or with lipophilic preparations like curing