Curcuminoids have poor bioavailability and require encapsulation or lipophilic preparations to achieve physiological effects.

“curcuminoids including curcumin in turmeric are very poorly bioavailable because your body wants to detoxify them and get them out of your body as quickly as possible so in order to get meaningful doses that actually achieve any physiological effect which i would argue is negative in the first place uh many of these need to be packaged this must be packaged with either piperine and we'll talk about the dangers of that later on in this video or with lipophilic preparations like curing”