Peter Attia· MD
but then a whole literature showing what distress in blue corticoids do there they mess with the dopamine system it's less clean of a story than a make the lower hippocampus but in ways that predispose towards the two big psychiatric diseases of screwed up dopamine systems number one addiction more vulnerability to addiction harder to get off of addictive substances number two depression depression is a disease on a certain level dopamine depletion it's a disease of inability to feel pleasure and hadou Nia and that's the neuro chemistry of the link between chronic stress and why that increases a likelihood of the first three four episodes of major depression