Rhonda Patrick· PhD
So you come to me and you say, “I’m just not responsive to antidepressants.” What’s actually happening is that those antidepressants are a absolutely non-optimal intervention for you, right?
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The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
So you come to me and you say, “I’m just not responsive to antidepressants.” What’s actually happening is that those antidepressants are a absolutely non-optimal intervention for you, right?
Every Sunday: the week’s new conflicts and verdict changes — and nothing else.
Native comments, Twitter mentions, and Reddit threads about this claim — surfaced together so the conversation isn't fragmented across platforms.
Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
Would love a "what would change this verdict" RSS feed. Sign me up if it exists.
Twenty five percent of people that are depressed will do much worse with an antidepressant than they would with a sugar pill.