Peter Attia· MD
it's overwhelmingly the genetics is the dominant factor and yes deterministic and maybe there are some epigenetic influences
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it's overwhelmingly the genetics is the dominant factor and yes deterministic and maybe there are some epigenetic influences
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but i think you have to be careful with your language so it's not just genetically susceptible i mean the genes are there and they're are these deterministic they're that they're causing autism there might be some environmental influences that could that could affect expression through epigenetics but uh it's not so simple as to say genetic susceptibility i don't think it's it's quite i don't think it's quite that straightforward
so just to take a step back first then just to kind of talk about the cause of autism like the genetics and the environmental piece so just to make it really clear like the word autism describes a constellation of symptoms there are many many causes for autism there isn't a single cause what causes autism is very complex and we actually have more questions than answers it's felt though that it is like a sort of like a a 10 hit model meaning like um and that we don't know that the number is 10 but the idea that there's multip it's not a two hit model it's not a two- hit model it's a there's many factors involved and it's almost felt like it's Gene Gene Gene environment environment environment and then now it's like epigenetics epigenetics epigenetics and so it's multiple hits and the Order of the hits and the timing of the hits are also felt to be very important
what causes autism is very complex and we actually have more questions than answers it's felt though that it is like a sort of like a a 10 hit model meaning like um and I that we don't know that the number is 10 but the idea that there's multiple it's not a two hit model it's not a two- hit model it's a there's many factors involved and it's almost felt like it's Gene Gene Gene environment environment environment and then now it's like epigenetics epigenetics epigenetics and so it's multiple hits and the Order of the hits and the timing of the hits are also felt to be very important