Sequencing the genome often involves piecing together overlapping DNA fragments rather than reading a continuous strand.

“in many cases we have pieces of it and we have to informatically put the pieces back together and put it back into the right order in some cases that's because we have overlap between those pieces and so we can see based on overlap this is the first piece that must be the second piece that the third piece based on the overlaps and so we make these things called contigs or contiguous sequences of DNA and put the puzzle and the pieces together in that way”