The Yamanaka factor reprogramming process creates a unique cellular state that may generate new stem cells capable of participating in developmental processes.

“What I think you do when you do a reprogramming event and you were able to exert something that looks like youthful biology you may have actually just created new you stem cells that are able to somehow pick up the music developmentally and participate that's sort of different than youth it's a bit of a sort of cell transplant II sort of thing although done by the delivery of genes”