Vaginal estrogen preparations can alleviate genital and urinary symptoms in breast cancer patients without significant systemic absorption.

“for instance patient has osteoporosis we have very good non hormonal options to treat osteoporosis um patient has hot flashes and night sweats there are non hormonal options to address those in fact the FDA just approved a drug a few months ago uh to try and treat hot flashes um uh uh um genital symptoms uh genital urinary symptoms sexual health issues were actually rather liberal about using genital uh preparations of um estrogen so vaginal estrogen creams and things like that that can alleviate some of the discomfort or other symptomatology without giving significant systemic absorption”