Anastrozole can manage high estradiol levels, which may be beneficial for bone health and mood if not exceeding 50-60 or causing symptoms.

“if estradiol levels do get a little too high they can be managed with a drug that blocks that conversion the drug is known as Anastrozole again I personally am not a big fan of using it because I find you really don't need to use it in most men in fact it's nice to have the estradiol levels go up because you want it for bone health you want it for mood you want it for all of those other reasons so we will typically not use Anastrozole unless the estradiol level is in excess of 50 55 or even 60 unless we are seeing symptoms that we would attribute to that”