The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
the women who had taken hormones before being randomized on the study who were randomized to placebo had a lower expected risk of breast cancer than women who had never taken hormones if you take the women who had taken hormones before going on the study and removed them from the control group you find no increased risk when you compare the women who got the hormones with the residual women in the control group
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Native comments, Twitter mentions, and Reddit threads about this claim — surfaced together so the conversation isn't fragmented across platforms.
Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
Would love a "what would change this verdict" RSS feed. Sign me up if it exists.
when you compare the women who were randomized to the two hormones compared with the women who were randomized to placebo on the estrogen only arm there was no increased risk even among the women who were randomized to the two hormones it was because there was a lower than expected risk among the control group who were randomized to the two hormones that you had what looked like an increased risk not a statistically significant one but an increased risk