A structured 2-year exercise protocol involved approximately 5-6 hours of total training per week, scaling up in the first year and maintained in the second.

“so yeah as you mentioned this was a two-year study which again like if anybody's familiar with exercise physiology research like doing a 2-year exercise intervention is pretty incredible to get those participants to adhere to that regimen um I can't remember how many participants were in that study right now but um I think it was you know up somewhere around 200 maybe but they had a pretty pretty decent number of participants um but it involved a two-year commitment and they didn't start them out right away doing everything that they were doing at the end but they scaled up their exercise gradually throughout the two years by year one they were kind of you know reaching their Peak exercise and then they maintain them for the second year and so what this involved was eventually you know doing about 5 to six hours of aerobic exercise or I guess it was total training per week was kind of 5 to six hours”