but i would say that overall it does appear to be very safe you know that's something that we're we've been interested in for a long time i i do think that you know as you as with anything when you give a a drug in a large you know clinical trial you start to see you know some side effects that you've never seen before so my guess is is that it when it becomes more and more and more popular we will find there will be certain rare events that we've never seen before but i think in the actual studies that have been done we see it to be overall relatively safe