Antioxidants taken with exercise can erase some of the beneficial effects of exercise, suggesting reactive oxygen species play an important signaling role in exercise adaptation.

“antioxidants on top of exercise almost prevents or racist some of the beneficial effects of exercise and the authors concluded that things like reactive oxygen species are probably playing an important signaling role as well that helps in the adaptation you need some of those sparks in order to turn on new programs that are net beneficial so if you erase those sparks yet you prevent the full benefit of exercise”