Exercise raises proteins that bind to IGF-1, reducing its bioavailability to cancer-forming cells, and increases amino acid uptake into skeletal muscle, reducing circulating IGF-1.

“exercise also raises levels of proteins that bind to igf-1 and reduce its bioavailability to damage cells that could potentially form cancer cells exercise alone causes more amino acids to be taken up into skeletal muscle which also has the effect of reducing circulating igf-1”