Rhonda Patrick· PhD
So, I would fast a lot and then I would typically try...if I fast for 16 hours, so I do a lot intermittent fasting as well, then that would get me back in right away.
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The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
So, I would fast a lot and then I would typically try...if I fast for 16 hours, so I do a lot intermittent fasting as well, then that would get me back in right away.
Every Sunday: the week’s new conflicts and verdict changes — and nothing else.
Native comments, Twitter mentions, and Reddit threads about this claim — surfaced together so the conversation isn't fragmented across platforms.
Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
Would love a "what would change this verdict" RSS feed. Sign me up if it exists.
In terms of entering ketosis, if you were to do it 14 hours, it’s not enough to really gain significant ketosis. You start seeing this at about 16 hours where your level will slowly rise.
Time-restricted eating produces fat loss independent of total calories.
A 72-hour fast measurably improves autophagy markers in healthy adults.
One-meal-a-day (OMAD) eating patterns increase all-cause mortality in long-running cohort data.
Eating the largest meal before 3pm improves 24-hour glucose vs. an evening-heavy schedule, calorie-matched.