Rhonda Patrick· PhD
And from the Valter Longo's research at UCLA, at least in animals, in mice, he's shown that it takes 48 hours of intermittent fasting to activate that whole autophagy system robustly and to increase hematopoiesis.
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Direct evidence is thin. The claim is plausible and aligns with adjacent findings, but there isn't yet a body of high-quality work that would let us call it well-supported on its own terms.
And from the Valter Longo's research at UCLA, at least in animals, in mice, he's shown that it takes 48 hours of intermittent fasting to activate that whole autophagy system robustly and to increase hematopoiesis.
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Time-restricted eating produces fat loss independent of total calories.
A 72-hour fast measurably improves autophagy markers in healthy adults.
One-meal-a-day (OMAD) eating patterns increase all-cause mortality in long-running cohort data.
Eating the largest meal before 3pm improves 24-hour glucose vs. an evening-heavy schedule, calorie-matched.