The evidence is convergent. Multiple independent sources reach the same conclusion, the underlying mechanism is well-characterized, and even the field's most cautious voices treat it as worth doing.
and the next day after um fasting in the sense of not eating anything that produced insulin they were like through the roof they went up to like 1300 which is like crazy high um but that always happens during a fast is free fatty acids go up
Every Sunday: the week’s new conflicts and verdict changes — and nothing else.
Native comments, Twitter mentions, and Reddit threads about this claim — surfaced together so the conversation isn't fragmented across platforms.
Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
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for example your free fatty acids get into the diabetic range so if you show that to somebody they think oh my god your ear diabetic and you're like really my insulin is unmeasurable my glucose is 60 milligrams per deciliter yes my FFA is two millimolar but my BHB is you know seven or you know five millimolar isn't it possible that what you're seeing is an incredible turnover of lipolysis and so yeah there's a lot of free fatty acid there but it's in motion it's in transit versus what I think is probably happening in the person with high FFA s who's got diabetes which is a much more stagnant form right of elevated FFA
by about seven days into a prolonged fast you pretty much reach a steady state you've got a pretty consistent flux of triglyceride into free fatty acid out of the fat cell you reach a steady state level of beta hydroxy butyrate acetoacetate and glucose such that basically the sum total of them in millimolar concentrations is about preserved to where you would be non fasting like
Time-restricted eating produces fat loss independent of total calories.
A 72-hour fast measurably improves autophagy markers in healthy adults.
One-meal-a-day (OMAD) eating patterns increase all-cause mortality in long-running cohort data.
Eating the largest meal before 3pm improves 24-hour glucose vs. an evening-heavy schedule, calorie-matched.