The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
we know that with fasting with a ketogenic diet we can flip it on and off when I am eating a steak with lots of leucine I am turning mTOR on and then in the 16 18 hours of the day that I am fasting with only water my mTOR is getting shut off because there's no inputs
Every Sunday: the week’s new conflicts and verdict changes — and nothing else.
Native comments, Twitter mentions, and Reddit threads about this claim — surfaced together so the conversation isn't fragmented across platforms.
Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
Would love a "what would change this verdict" RSS feed. Sign me up if it exists.
with fasting with a ketogenic diet we can flip it on and off
if i'm eating a ketogenic carnivore diet and i'm simulating with leucine it's more precise it's on less and it's on for a shorter amount of time and there's not as much carryover so if i'm doing a ketogenic carnivore diet maybe like our ancestors would have done just eating mostly animals and getting lots of protein i'm turning mtor on for six hours a day and then i have a fasting window where it's off all day
Time-restricted eating produces fat loss independent of total calories.
A 72-hour fast measurably improves autophagy markers in healthy adults.
One-meal-a-day (OMAD) eating patterns increase all-cause mortality in long-running cohort data.
Eating the largest meal before 3pm improves 24-hour glucose vs. an evening-heavy schedule, calorie-matched.