The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
caloric restriction in general will cause our thyroid to change you know anyone that's talked about fasting from Peter attea to anyone else in space when you check the thyroid hormone the thyroid hormones go down the free t3 goes down the reverse t3 goes up and I'm gonna show a diagram of the normal thyroid sequence and show you guys what all those things look like in a moment but you know fasting and caloric restriction will change thyroid hormones in a normal fashion
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Native comments, Twitter mentions, and Reddit threads about this claim — surfaced together so the conversation isn't fragmented across platforms.
Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
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In fact one of the things I used to notice when I did frequent fasting because I would fast for say a week at a time and I would always check my blood pre and post is how much my thyroid function deteriorated during that period of time and it wasn't just a deterioration in the usual metrics such as TSH and T4 it was how much my free T3 and reverse T3 changed in fact the ratio of my free T3 to reverse T3 might go from 0.25 which is pretty normal to 0.05 or less in just a five to seven day fast and you know I would say about half of that was due to the reduction in T3 and the majority of that was due to the increase in Reverse T3
the ratio of my free T3 to reverse T3 might go from 0.25 which is pretty normal to 0.05 or less in just a five to seven day fast and you know I would say about half of that was due to the reduction in T3 and the majority of that was due to the increase in Reverse T3
in fact one of the things I used to notice when I did frequent fasting because I would fast for say a week at a time and I would always check my blood pre and post is how much my thyroid function deteriorated during that period of time and it wasn't just a deterioration in the usual metrics such as TSH and T4 it was how much my free T3 and reverse T3 changed in fact the ratio of my free T3 to reverse T3 might go from 0.25 which is pretty normal to 0.05 or less in just a five to seven day fast and you know I would say about half of that was due to the reduction in T3 and the majority of that was due to the increase in Reverse T3
Time-restricted eating produces fat loss independent of total calories.
A 72-hour fast measurably improves autophagy markers in healthy adults.
One-meal-a-day (OMAD) eating patterns increase all-cause mortality in long-running cohort data.
Eating the largest meal before 3pm improves 24-hour glucose vs. an evening-heavy schedule, calorie-matched.