Paul Saladino· MD
in this study that your colleague did with the rats or the mice that were fed in a small window were they calorie restricted or today were they isocaloric and in a smaller amount of time they were
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The evidence is convergent. Multiple independent sources reach the same conclusion, the underlying mechanism is well-characterized, and even the field's most cautious voices treat it as worth doing.
in this study that your colleague did with the rats or the mice that were fed in a small window were they calorie restricted or today were they isocaloric and in a smaller amount of time they were
Every Sunday: the week’s new conflicts and verdict changes — and nothing else.
Native comments, Twitter mentions, and Reddit threads about this claim — surfaced together so the conversation isn't fragmented across platforms.
Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
Would love a "what would change this verdict" RSS feed. Sign me up if it exists.
These days, as you're aware, intermittent fasting seems to kick these longevity genes into action. The sirtuins still come on, but you don't always need to be hungry.
Time-restricted eating produces fat loss independent of total calories.
A 72-hour fast measurably improves autophagy markers in healthy adults.
One-meal-a-day (OMAD) eating patterns increase all-cause mortality in long-running cohort data.
Eating the largest meal before 3pm improves 24-hour glucose vs. an evening-heavy schedule, calorie-matched.