Rhonda Patrick· PhD
There's also some evidence that a fasting or ketogenic diet could be beneficial for people with autoimmune diseases, such as multiple sclerosis.
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The evidence is convergent. Multiple independent sources reach the same conclusion, the underlying mechanism is well-characterized, and even the field's most cautious voices treat it as worth doing.
There's also some evidence that a fasting or ketogenic diet could be beneficial for people with autoimmune diseases, such as multiple sclerosis.
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Fasting-like diet kills autoimmune cells & replaced them with healthy cells & improved symptoms in MS patients.
And these leads to about 20% of the mice being disease-free, right? So, I mean, 20% of mice are cured from this autoimmunity, which is very much like multiple sclerosis.
The fasting-mimicking diet causes the white blood cells, so the immune cells, as I mentioned earlier, to be destroyed, partially destroyed. And then, it turns on the stem cells. And when you make new cells, of course, they're no longer autoimmune, right? So, the original cells are autoimmune, they're attacking the oligodendrocytes in the spinal cord. The new cells, we've shown they're no longer immune.
Yeah, but I can tell you, we've now confirmed it with all the autoimmune diseases. So I think it's going to be applicable to many autoimmune diseases.
he is a variety of clinical studies where he has looked at the effects of basically not eating food for a prolonged period of time which is around 48 at least 48 hours and he's looked at the effects of that on for example autoimmune related diseases so people that had multiple sclerosis they were doing in that case it wasn't actually a fast they were doing a fasting mimicking diet so it was a diet that was sort of had a very specific callewaert content and macronutrient composition that act activated a lot of the same molecular pathways that fasting does and it improved a variety it improved disease status in the multiple sclerosis patients
what walter is shown in a lot of animal studies is that immune cells that are dysfunctional those are preferentially killed off and replaced by healthy new non auto immune cells which is amazing
Time-restricted eating produces fat loss independent of total calories.
A 72-hour fast measurably improves autophagy markers in healthy adults.
One-meal-a-day (OMAD) eating patterns increase all-cause mortality in long-running cohort data.
Eating the largest meal before 3pm improves 24-hour glucose vs. an evening-heavy schedule, calorie-matched.