The evidence is convergent. Multiple independent sources reach the same conclusion, the underlying mechanism is well-characterized, and even the field's most cautious voices treat it as worth doing.
now when glucose is no longer there and you were talking about prolonged fasting and glycogen depletion the brain becomes very efficient in extracting ketone bodies through the blood-brain barrier to maintain its firing and to avoid someone from getting into a coma-like state
Every Sunday: the week’s new conflicts and verdict changes — and nothing else.
Native comments, Twitter mentions, and Reddit threads about this claim — surfaced together so the conversation isn't fragmented across platforms.
Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
Would love a "what would change this verdict" RSS feed. Sign me up if it exists.
George I I could have sworn George Cahill demonstrated in those very famous fasting studies uh Circa you know 1960s 1970s that even in the presence of glucose the brain was still taking up significant beta hydroxy butter rate
What most ipeople did not realize is that the concentration of beta-hydroxybutyrate in your plasma or in your brain during fasting can go in the millimolar range very quickly.
Time-restricted eating produces fat loss independent of total calories.
A 72-hour fast measurably improves autophagy markers in healthy adults.
One-meal-a-day (OMAD) eating patterns increase all-cause mortality in long-running cohort data.
Eating the largest meal before 3pm improves 24-hour glucose vs. an evening-heavy schedule, calorie-matched.