Rhonda Patrick· PhD
The NEJM study is not a good comparison of CR vs TRE with a ~2.5-hour difference in eating windows.
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We can't find evidence that holds up here. Proponents are reasoning from mechanism or analogy rather than direct human data, and the most credible skeptics raise objections we can't dismiss.
The NEJM study is not a good comparison of CR vs TRE with a ~2.5-hour difference in eating windows.
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Time-restricted eating produces fat loss independent of total calories.
A 72-hour fast measurably improves autophagy markers in healthy adults.
One-meal-a-day (OMAD) eating patterns increase all-cause mortality in long-running cohort data.
Eating the largest meal before 3pm improves 24-hour glucose vs. an evening-heavy schedule, calorie-matched.