Peter Attia· MD
now I actually think that perhaps even doing periodic you know prolonged fasts or a better way of doing that because you can you can get that igf-1 boost and you can get the the lower igf-1 among other things that occur
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The evidence is convergent. Multiple independent sources reach the same conclusion, the underlying mechanism is well-characterized, and even the field's most cautious voices treat it as worth doing.
now I actually think that perhaps even doing periodic you know prolonged fasts or a better way of doing that because you can you can get that igf-1 boost and you can get the the lower igf-1 among other things that occur
Every Sunday: the week’s new conflicts and verdict changes — and nothing else.
Native comments, Twitter mentions, and Reddit threads about this claim — surfaced together so the conversation isn't fragmented across platforms.
Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
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So, doing the fasting, the IGF-1 goes down, and so that store and that does everything else. But during the refeeding, IGF-1 goes up, and IGF-1 is the driver of all this regeneration.
Time-restricted eating produces fat loss independent of total calories.
A 72-hour fast measurably improves autophagy markers in healthy adults.
One-meal-a-day (OMAD) eating patterns increase all-cause mortality in long-running cohort data.
Eating the largest meal before 3pm improves 24-hour glucose vs. an evening-heavy schedule, calorie-matched.