Fasting has a powerful anti-inflammatory effect, demonstrated by a decrease in the NLRP3 inflammasome and IL1 Beta gene expression after a 24-hour fast.

“nor should it be surprising that fasting has a powerful anti-inflammatory effect. There’s some beautiful data in animals, but also beautiful data in human too. There was a study in 19 normal volunteers, and they looked at the effect of a, like a 24-hour fast on something called the NLRP3 inflammasome. It’s the intercellular thing that connects up and it activates inflammation, turns on this thing called IL1 Beta. So you fast, and that the expression, the gene expression for that complex, just goes down down down down down.”