Paul Saladino· MD
but if you look at the results in more detail you find that testosterone and insulin-like growth factor igf-1 decreased significantly in time-restricted feeding with no changes in the control group adiponectin increased in the time-restricted feeding while the total leptin decreased although not when adjusted for the fat mass triota thyronine which is t3 decreased in the time-restricted feeding group but no changes were detected in the tsh total cholesterol hdl ldl or triglycerides resting energy expenditure was unchanged but a significant decrease in the respiratory ratio was observed in the trf group probably because they were shifting more toward fat metabolism and the rq was changing but the changes in the testosterone and the igf-1 are what concern me along with the t3