Paul Saladino· MD
there's also some people who hypothesize that increased apoptosis or apoptosis depending however you want to say it is leading to breakdown of cells cellular house cleaning and the breakdown of cells could be really releasing purines which are metabolized but in general this is a study from uh also from 1965 there's another one i found from 1925 showing that when you look at this ketosis and fasting the amount of protein breakdown the nitrogen balance in the blood doesn't go positive it doesn't look like a whole lot more proteins are actually being broken down which kind of argues against the idea that uric acid is rising because of apoptosis or breakdown