Peter Attia· MD
But my fast coming up this week I am not taking metformin.
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The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
But my fast coming up this week I am not taking metformin.
Every Sunday: the week’s new conflicts and verdict changes — and nothing else.
Native comments, Twitter mentions, and Reddit threads about this claim — surfaced together so the conversation isn't fragmented across platforms.
Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
Would love a "what would change this verdict" RSS feed. Sign me up if it exists.
One of the things I do when I'm fasting is I'm not taking those things obviously so any period of fasting longer than a day those things get stopped again
There was no change in any supplement or medication that I took during... Yeah. inhibit hepatic glucose output when you were fasting, but I also realized I didn't want to create any artifact. Um, and I wasn't obviously concerned about having hypoglycemia as a response to metformin.
Time-restricted eating produces fat loss independent of total calories.
A 72-hour fast measurably improves autophagy markers in healthy adults.
One-meal-a-day (OMAD) eating patterns increase all-cause mortality in long-running cohort data.
Eating the largest meal before 3pm improves 24-hour glucose vs. an evening-heavy schedule, calorie-matched.