Akkermansia tends to increase with ketosis and fasting, suggesting a fiber-free diet supporting the gut epithelium with ketones or isobutyrate may not deplete the gut mucus layer.

“acromanzia that microbe that feeds on the mucus layer tends to increase with ketosis and fasting so typically uh if you're consuming a fiber-free diet but it's got lots of sugar and inflammatory things then yes you're definitely going to deplete the gut mucus layer if you're supporting your gut epithelium with ketones uh potentially isobutyrate uh i don't i don't see any reason that she would deplete the gut mucus layer and in fact the increase in the abundance of acromanzia would suggest that it it might even do the opposite right because how could you increase the abundance of acromancy if it didn't have the mucus to feed on during ketosis right right”