Biopsies are used to exclude autoimmune components, for clinical trials, and for diagnostic testing prior to procedures or surgery where cirrhosis status is critical.

“the time that we bring in biopsies um usually for anything oftentimes we'll get especially women with a positive Ana smooth muscle antibod some indication that there may be an autoimmune component so treatments are very different between the two so to exclude um a biomarker of interest in a population about 18 to 20% of people of of patients with masel d will have one of those positive biomarkers so we use it to exclude other types of diseases we also use it for clinical trials purposes um and then we use use it oftentimes in diagnostic testing prior to procedure prior to an elective surgery um prior to um an intervention that may or may not result in liver where you need to know about curosis before an abdominal surgery or a cardiothoracic surgery might be done”