The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
is there then a relationship between MTHFR and propensity to fatty liver disease given that a subset of patients are gonna be burning through choline quicker and therefore have less choline to do its job in the liver I would expect that that could be the case off the top of my head I don't know if data on that
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Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
Would love a "what would change this verdict" RSS feed. Sign me up if it exists.
as long as you have enough choline in the diet where you have some precursor to make choline whether it's sugar alcohol fat as long as you have enough choline in the diet you can clear those triglycerides out of the liver
that's what I would believe based on all of the animal experiments that were done
do you believe that it is more driven by a fat accumulation in the liver problem or choline being less prevalent in our diets and therefore more of a clearance problem it's hard to make an either/or question about it because it comes down to fat in versus fat out and choline is such an overwhelming factor in the fat out part of the equation