Factors that can negatively impact the microbiome include overuse of antibiotics, overly restrictive diets, excessive sanitization, and lack of exposure to environmental microbes.

“so in her case antibiotics might have played a role massively restricted eating so we both had really restrictive diets so remember the whole rabbit starvation she was doing the same thing so just over restriction over sanitizing hands over washing hands like never getting anything that's dirty yeah I mean just making literally every mistake that you can make with your microbiome”