Peter Attia· MD
as we move into this next phase of complexity I think what's pretty clear is it's not the mature HDL particle you know when we measure HDL cholesterol that's what we're measuring is the cholesterol in the mature particle that's almost certainly not the particle that is driving this first step of the efflux of the cholesterol from the foam cell and the macrophage and and that's maybe why simplistically raising HDL cholesterol like with C to be inhibition and doesn't actually reduce the atherosclerto cardiovascular disease events but are there other ways more creatively that we might be able to drive that process