Mice eating a standard diet on a regular rhythm show rhythmic changes in gut microbiome composition, while continuous high-carb feeding reduces diversity.

“So in mouse experiments what we have seen is when mice eat a standard diet, a healthy diet, and they eat on a regular rhythm, so they eat mostly during nighttime because they're nocturnal, and eat less during daytime, the their gut...the microbiome composition changes nicely in a rhythmic fashion throughout the day. But when they eat this high carb diet continuously, then that diversity goes down, their gut is mostly populated by a few meso microbes.”